Amplatzer™ Amulet™
Left Atrial Appendage Occluder
Designed to treat patients with non-valvular atrial fibrillation (AFib) who are at risk of ischemic stroke, the Amplatzer Amulet LAA Occluder offers complete closure of the left atrial appendage (LAA) and immediately eliminates the need for oral anticoagulants.1
CLOSURE. ONCE AND FOR ALL.2,3
The Amplatzer Amulet LAA Occluder offers a dual seal design to treat virtually all morphologies and provide closure, once and for all.
For those patients who are either contraindicated for OACs or wish to discontinue use, LAAO with the Amulet occluder is a viable option to reduce their risk of stroke.
PATIENTS WHO BENEFIT
Life-long medication to reduce stroke risk is not an option for many patients. The Amplatzer Amulet LAA Occluder permanently closes this primary stroke pathway without requiring these patients to endure the challenges of oral anticoagulants (OACs).
Why Amulet? Meet Terry
Listen to Terry, who received the Amplatzer Amulet Occluder, speak about how the procedure improved her life.
"I started feeling better immediately. I've been going ever since. Nothing keeps me down."
The Amulet occluder can be a good option1, 4-6 for patients who:
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ARE CONTRAINDICATED TO
TO OACs
For patients with poorly controlled or uncontrolled hypertension, oral anticoagulants are contraindicated. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants that are not a safe choice for these patients.
Regina (AGE 55)
Regina, who has NVAF and a CHA2DS2-VASc score is 4, has had poorly controlled hypertension for 10 years. Her doctor wants to reduce her stroke risk without jeopardizing her safety.
NVAF patients with poorly controlled hypertension should know that there is an alternative.
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HAVE HAD
A
BLEEDING EVENT
The long-term bleeding risks associated with OACs, such as Warfarin are particularly concerning for patients with active lifestyles or occupations. Amplatzer Amulet Occluder supports the freedom to have a more active lifestyle.
Rita (AGE 65)
Rita has NVAF and a CHA2DS2-VASc score of 4. She is reducing her stroke risk without having to limit her travel and play with her grandchildren.
NVAF patients who want to remain active should know that there is an alternative.
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ARE AT
HIGH
RISK FOR FALLS
A fall can erode a patient’s confidence and willingness to engage in everyday tasks. It can also lead to a major bleeding event. Consider Amplatzer Amulet occluder when you or your patients are concerned about the risk of falls or bleeding.
Nathan (AGE 80)
Nathan, who has NVAF and a CHA2DS2-VASc score of 5, hit his head the last time he fell. He and his doctor want to reduce his stroke risk without increasing his risk for a major bleeding event.
NVAF patients at high risk for bleeding should know that there is an alternative.
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ARE AT RISK
FOR
DRUG INTERACTIONS
OACs are incompatible with treatments for many comorbidities including depression or arthritis. Amplatzer Amulet occluder is an alternative to oral anticoagulants that can increase the risk of drug interactions.
Michael (AGE 75)
Michael has Non-Valvular Atrial Fibrillation (NVAF) and a CHA2DS2-VASc score of 5. He is reducing his stroke risk without increasing his risk for drug interactions.
NVAF patients with comorbidities should know that there is an alternative.
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ARE NOT ADHERING TO ROUTINE MONITORING
Adverse effects, cost and monitoring can make compliance a challenge for patients. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants that can lead to noncompliance.
Sarah (AGE 73)
Sarah has NVAF and a CHA2DS2-VASc score of 4. She is reducing her stroke risk without having to take OACs for the rest of her life.
NVAF patients who struggle with compliance should know that there is an alternative.
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ARE CONTRAINDICATED
TO OACs
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</figure>
HAVE HAD
A
BLEEDING EVENT
</picture>
</figure>
ARE AT
HIGH
RISK FOR FALLS
</picture>
</figure>
ARE AT RISK
FOR
DRUG INTERACTIONS
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</figure>
ARE NOT ADHERING TO ROUTINE MONITORING
For patients with poorly controlled or uncontrolled hypertension, oral anticoagulants are contraindicated. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants that are not a safe choice for these patients.
Regina (AGE 55)
Regina, who has NVAF and a CHA2DS2-VASc score is 4, has had poorly controlled hypertension for 10 years. Her doctor wants to reduce her stroke risk without jeopardizing her safety.
NVAF patients with poorly controlled hypertension should know that there is an alternative.
The long-term bleeding risks associated with OACs, such as Warfarin, are particularly concerning for patients with active lifestyles or occupations. Amplatzer Amulet Occluder supports the freedom to have a more active lifestyle.
Rita (AGE 65)
Rita has NVAF and a CHA2DS2-VASc score of 4. She is reducing her stroke risk without having to limit her travel and play with her grandchildren.
NVAF patients who want to remain active should know that there is an alternative.
A fall can erode a patient’s confidence and willingness to engage in everyday tasks. It can also lead to a major bleeding event. Consider Amplatzer Amulet occluder when you or your patients are concerned about the risk of falls or bleeding.
Nathan (AGE 80)
Nathan, who has NVAF and a CHA2DS2-VASc score of 5, hit his head the last time he fell. He and his doctor want to reduce his stroke risk without increasing his risk for a major bleeding event.
NVAF patients at high risk for bleeding should know that there is an alternative.
OACs are incompatible with treatments for many comorbidities including depression or arthritis. Amplatzer Amulet occluder is an alternative to oral anticoagulants that can increase the risk of drug interactions.
Michael (AGE 75)
Michael has Non-Valvular Atrial Fibrillation (NVAF) and a CHA2DS2-VASc score of 5. He is reducing his stroke risk without increasing his risk for drug interactions.
NVAF patients with comorbidities should know that there is an alternative.
Adverse effects, the cost of non-vitamin K antagonist oral anticoagulants (NOACs), or the monitoring required when taking warfarin, often make compliance a challenge for patients. Amplatzer Amulet occluder is an alternative to life-long oral anticoagulants that can lead to noncompliance.
Sarah (AGE 73)
Sarah has NVAF and a CHA2DS2-VASc score of 4. She is reducing her stroke risk without having to take OACs for the rest of her life.
NVAF patients who struggle with compliance should know that there is an alternative.
For educational purposes only; not real patient cases.
KEY FEATURES
Dual Seal Technology
- Designed to seal all morphology types7
- Reduces the risk of stroke8
- Eliminates the need for OACs9
The Amplatzer Amulet occluder offers two mechanisms of closure designed to ensure complete occlusion.
Widest range of sizes ensure best LAA fit
The Amulet occluder offers 8 sizes and allows versatility to treat a broad range of LAA morphologies.
Treating the simplest to most complex morphologies
80%
of appendages have
more than 1 lobe10
NEARLY
50%
of appendages are chicken wing
anatomy which presents challenges
with a shallow landing zone11
Advance your LAAO practice with the Amulet™ Steerable Delivery Sheath.
Unmatched features for precision and control.
The Amulet Steerable Delivery Sheath enables optimal placement of the Amplatzer Amulet LAA Occluder.
Physician Education
Hear from physicians how the Amplatzer Amulet occluder can benefit physicians and help patients live longer, fuller lives.
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MAT-2111179 v12.0 | Item approved for U.S. use only.